中文

Thondar Academy

Multimodal imaging in a severe case of hydroxychloroquine toxicity
来源:Ophthalmic Surg Lasers Imaging Retina . 2015 Mar;46(3):377-9. doi: 10.3928/23258160-20150323-14. | 作者:Kavita V Bhavsar, Lekha K Mukkamala, K Bailey Freund | 发布时间: 2015-03-01 | 493 次浏览 | 分享到:
Authors and their organizations：
Kavita V Bhavsar, Lekha K Mukkamala, K Bailey Freund


Abstract
Retinal toxicity from hydroxychloroquine (HCQ) can be detected most readily on fundus autofluorescence, spectral-domain optical coherence tomography, and multifocal electroretinogram. The authors describe a case of a 60-year-old woman with a history of systemic lupus erythematosus undergoing HCQ treatment for 30 years who presented with visual loss over several years. Examination and multimodal imaging showed bilateral retinal pigment epithelium (RPE) changes in a bull's-eye distribution associated with cystoid macular edema. A novel imaging modality, multi-spectral imaging, appeared sensitive in detecting a bull's-eye pattern of RPE disturbance involving the entire macular region of both eyes. Cessation of drug was advised with close follow-up.



Visit the source of the original