State Key Laboratory of Ophthalmology，Zhongshan Ophthalmic Center，Sun Yat-sen University，Guangzhou 510060，China

Abstract

【Objective】To evaluate the repeatability and agreement of multispectral refraction tomography（MRT， Thondar，Shenzhen，China）in measuring retinal refraction under cycloplegic condition in children.

【Methods】Children aged 8 to 10 years were recruited. Objective refraction and axial length measurements were performed after sufficient paralysis. Retinal refraction was measured twice by one examiner using MRT. The retinal deviation value（RDV）and relative retinal deviation value（RRDV）were used to describe retinal refraction and relative retinal refraction. Wilcoxon Signed Rank Test，the intraclass correlation coefficient（ICC）and 95% limits of agreements（LoA）were used to evaluate the repeatability and agreement between two consecutive measurements and between MRT and autorefractor.

【Results】A total of 146 children with mean age of 9.22±0.61 years were enrolled. Central refraction between auto refractor and MRT showed good agreement，with an ICC value of 0.94，（95%CI［0.92，0.96］）. RDV provided excellent repeatability，with lowest ICC value of 0.93（95%CI=［0.91，0.95］）. The RRDV demonstrated descending ICC value within 30°eccentricity（lowest ICC=0.37，95%CI=［0.12，0.54］in RDV-15）and showed good repeatability beyond 30°（lowest ICC = 0.87（95%CI= ［0.81，0.90］）. Neither RDV nor RRDV showed statistically significant differences between measurements.（All P>0.05）

【Conclusion】MRT provides repeatable measurements of retinal peripheral refraction under cycloplegic conditions in schoolchildren with mild refractive error.