Authors and their organizations：
Xiangyue Zheng 1, Dejin Cheng 2, Xiaoli Lu 1, Xiaoyi Yu 1, Yuting Huang 1, Yujie Xia 3, Chuni Lin 3, Zhao Wang 3
1 Department of Ophthalmology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
2 Department of Nephropathy, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
3 First Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou, China.
Objective:
To observe the associations between regional peripheral refraction and myopia development in young Chinese people.
Methods:
Two hundred and forty-one young adult subjects (21 emmetropes, 88 low myopes, 94 moderate myopes, and 38 high myopes) aged 18-28 years were included, and only the right eyes were tested. Eye biometrics were measured before pupil dilation using the Lenstar. Relative peripheral refractive errors (RPRE) were measured after pupil dilation using multispectral refractive topography (MRT), at nine retinal eccentricities: 0-5, 5-10, 10-15, 15-20, 20-25, 25-30, 30-35, 35-40, and 40-45 degrees.
Results:
In this study, RPRE increased with eccentricity, and it shows a growing trend with the increase of the degree of myopia among emmetropia, low myopia and moderate myopia groups, and RPRE varied with myopia severity at eccentricities between 20 and 35 degrees only. In addition, axial length (AL) and RPRE were positively correlated between 20 and 45 degrees, and AL was an independent risk factor for RPRE between 20 and 35 degrees.
Conclusion:
These findings indicate that the eccentricities between 20 and 35 degrees RPRE may be closely related to refractive development and eye growth in young Chinese people.
